特立氟胺英文怎么写
Teriflunomide belongs to a class of drugs known as pyrimidine synthesis inhibitors. It works by inhibiting an enzyme called dihydroorotate dehydrogenase, which is necessary for the production of DNA and RNA in rapidly dividing cells, such as lymphocytes. By inhibiting this enzyme, teriflunomide decreases the number of activated immune cells in the central nervous system, reducing the inflammation that occurs in MS. MS is a chronic autoimmune disease that affects the central nervous system, causing inflammation, demyelination, and neurodegeneration. It can lead to various symptoms such as muscle weakness, difficulty walking, pain, and problems with coordination and balance. Teriflunomide is indicated for the treatment of relapsing forms of MS, which includes relapsing-remitting MS and active secondary progressive MS with relapses. The use of teriflunomide can lead to some side effects, which vary in their severity and frequency. Common side effects include diarrhea, nausea, hair thinning, headache, and increased blood pressure. Rare but serious side effects include liver problems, bone marrow suppression, and an increased risk of infections. Regular monitoring of liver function and blood cell counts is recommended during treatment. Certain precautions should be considered before starting teriflunomide. It is contraindicated in pregnant women or those planning to become pregnant due to the risk of fetal harm. Females of childbearing potential should use effective contraception during treatment and undergo blood tests to confirm the drug is no longer present in their system before attempting pregnancy. Teriflunomide may also interact with other medications, so it is important to inform the healthcare provider about all the drugs being used. Teriflunomide is usually taken orally once daily and comes in tablet form. The initial loading dose is 7-14 mg followed by a maintenance dose of 14 mg. The exact dosing regimen is determined by the prescribing physician based on the individual patient's condition. In conclusion, teriflunomide is an effective treatment option for relapsing forms of MS. By inhibiting the proliferation of immune cells in the central nervous system, it helps to reduce inflammation and delay disease progression. However, it is essential to be aware of its side effects and precautions. Regular monitoring and open communication with the healthcare provider are crucial for a successful treatment outcome with teriflunomide.
陈志明 | 问药网药师
回答时间 2023-07-24 16:22:12