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The Introduction and Effects of Cinacalcet

发布时间:2023-06-15 18:59:00 阅读:88 来源:问药网
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盐酸西那卡塞

盐酸西那卡塞 生产厂家:印度Intas 功能主治:强效CYP2D6抑制剂,治疗慢性肾病甲状腺癌甲状腺亢进 用法用量:用法用量  口服给药,应整片吞服,不能掰开,与食物同服或餐后短时间内服用,剂量应个体化。  用于透析CKD患者的继发性甲状旁腺功能亢进:推荐开始剂量为每日1次,每次30mg,1周内检测血钙和血磷水平,1~4周检测PTH水平。  每日剂量调整为60mg、90mg、120mg、180mg的时间均不得少于2~4周。  患者PTH浓度应控制在150~300pg/ml。  用于治疗甲状旁腺癌患者的高钙血症:推荐开始剂量为每日2次,每次30mg。  剂量调整每2~4周一次,根据血钙浓度,剂量可调整为每次60mg,每日2次;  每次90mg,每日2次;  每次90mg,每日3~4次。
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  Cinacalcet, also known as cinacalcet hydrochloride, is a medication used to treat hyperparathyroidism, a condition caused by overactive parathyroid glands that produce too much parathyroid hormone. This hormone regulates calcium and phosphorus levels in the body, and when it is overproduced, it can lead to weakened bones, digestive problems, and kidney dysfunction. Cinacalcet works by reducing the amount of parathyroid hormone released by the glands, thus controlling the levels of calcium and phosphorus in the blood.
  Apart from hyperparathyroidism, cinacalcet is also used to treat secondary hyperparathyroidism in patients with chronic kidney disease undergoing dialysis. This condition occurs when the kidneys are unable to excrete enough phosphorus, leading to increased levels in the blood that stimulate the parathyroid glands to produce excess hormone. Cinacalcet can help reduce the levels of parathyroid hormone while simultaneously lowering serum phosphorus levels.
盐酸西那卡塞  Furthermore, cinacalcet is also used for the treatment of parathyroid carcinoma, a rare type of tumor that affects the parathyroid glands. In such cases, traditional surgical methods may not be effective at controlling the symptoms, and cinacalcet may be used to lower the amount of parathyroid hormone released by the tumors.
  The recommended dosage of cinacalcet varies depending on the condition being treated and the patient's level of kidney function. However, it is usually taken orally once daily with or without food. The most common side effects of cinacalcet include nausea, vomiting, decreased appetite, and headache. These side effects typically subside within a few days of starting the medication and are generally mild in nature.
  In conclusion, cinacalcet is an effective medication for the treatment of hyperparathyroidism, secondary hyperparathyroidism in patients with chronic kidney disease, and parathyroid carcinoma. It works by reducing the amount of parathyroid hormone released by the glands, thus controlling the levels of calcium and phosphorus in the blood. While it may cause some mild side effects, they are generally well-tolerated and typically subside within a few days. It is important to discuss the risks and benefits of cinacalcet with your doctor before beginning treatment.