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Ambisome服用注意什么

发布时间:2023-12-22 15:34:24 阅读:1240 来源:问药网
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安必素

安必素 生产厂家:迈兰(Mylan)制药有限公司 功能主治:一线抗真菌药物,治疗深部真菌感染有效率高 用法用量:用法用量  静脉用药:开始静脉滴注时先试以1~5mg或按体重一次0.02~0.1mg/kg给药,以后根据患者耐受情况每日或隔日增加5mg,当增至一次 0.6~0.7mg/kg时即可暂停增加剂量,此为一般治疗量。  成人最高一日剂量不超过1mg/kg,每日或隔1~2日给药1次,累积总量 1.5~3.0g,疗程1~3个月,也可长至6个月,视病情及疾病种类而定。  对敏感真菌感染宜采用较小剂量,即成人一次20~30mg,疗程仍宜长。  鞘内给药:首次0.05~0.1mg,以后渐增至每次0.5mg,最大量一次不超过1mg,每周给药2~3次,总量15mg左右。  鞘内给药时宜与小剂量地塞米松或琥珀酸氢化可的松同时给与,并需用脑脊液反复稀释药液,边稀释边缓慢注入以减少不良反应。  局部用药:气溶吸入时成人每次5~10mg,用灭菌注射用水溶解成0.2%~0.3%溶液应用;超声雾化吸入时本品浓度为0.01%~0.02%,每日吸入2~3次,每次吸入5~10ml;持续膀胱冲洗时每日以两性霉素B 5mg加入1000ml灭菌注射用水中,按每小时注入40ml速度进行冲洗,共用5~10日。  静脉滴注或鞘内给药时,均先以灭菌注射用水10ml配制本品50mg,或5ml配制25mg,然后用5%葡萄糖注射液稀释(不可用氯化钠注射液,因可产生沉淀),滴注液的药物浓度不超过10mg/100ml,避光缓慢静滴,每次滴注时间需6小时以上,稀释用葡萄糖注射液的pH值应在4.2以上。  鞘内注射时可取5mg/ml浓度的药液1ml,加5%葡萄糖注射液19ml稀释,使最终浓度成250μg/ml。  注射时取所需药液量以脑脊液5~30ml反复稀释,并缓慢注入。  鞘内注射液的药物浓度不可高于25mg/100ml,pH值应在4.2以上。
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Ambisome服用注意什么,Ambisome(AmBisome)的注意事项:1.如果发生严重的变态反应或过敏/类过敏反应,应立即中止输注。2.在服用含两性霉素B的产品期间,可能会发生其他与输液有关的严重反应。3.如果临床上出现肾功能显著下降或其他参数恶化,则应考虑减少剂量,中断治疗或中止治疗。4.在白细胞输注期间或之后不久,服用两性霉素B会可能出现急性肺毒性。5.对于糖尿病患者而言,每个小瓶中的AmBisome均含约900mg蔗糖。治疗糖尿病患者时应考虑到这一点。

Ambisome is a medication commonly used to treat fungal infections. It belongs to a class of drugs known as antifungals and is specifically designed to target and eliminate fungal infections in the body. However, like any medication, it is important to take certain precautions and follow specific guidelines to ensure its safe and effective use. In this article, we will explore some important considerations to keep in mind while taking Ambisome.

1. Follow the Prescribed Dosage:

One crucial aspect of using Ambisome properly is to strictly adhere to the prescribed dosage instructed by your healthcare provider. The dosage may vary based on the type and severity of the infection as well as individual factors. Do not exceed or reduce the prescribed amount without consulting your healthcare professional.

2. Administered via Intravenous Infusion:

Ambisome is typically administered through a slow intravenous infusion, which means it is delivered directly into your veins using an IV. It is essential to have this medication administered by a healthcare professional experienced in the administration of IV therapy. Follow the instructions provided by your healthcare provider regarding the duration and frequency of the infusion.

3. Maintain Hydration:

While on Ambisome treatment, it is important to maintain proper hydration. Drinking an adequate amount of fluids, as recommended by your healthcare provider, can help prevent potential side effects associated with the medication. Adequate hydration also supports the overall well-being of your body during the treatment.

4. Regular Monitoring and Blood Tests:

During the course of Ambisome treatment, your healthcare provider may order regular monitoring and blood tests to assess your response to the medication and to check for any potential side effects. It is essential to attend these appointments and follow through with any recommended tests to ensure your safety and optimize the effectiveness of the treatment.

5. Adverse Reactions and Side Effects:

Like any medication, Ambisome can have side effects. Common side effects may include fever, chills, headache, nausea, fatigue, or muscle pain. It is important to report any unusual or severe symptoms to your healthcare provider immediately. They can provide guidance and may adjust your treatment if necessary.

6. Drug Interactions:

Inform your healthcare provider about all medications, supplements, or herbal products you are currently taking before starting Ambisome. Certain medications may interact with Ambisome, potentially affecting its efficacy or increasing the risk of side effects. Your healthcare provider can determine any necessary adjustments or precautions to be taken.

7. Pregnancy and Breastfeeding:

If you are pregnant, planning to become pregnant, or breastfeeding, it is crucial to discuss the potential risks and benefits of Ambisome with your healthcare provider. They can provide guidance on the safest course of treatment for you and your baby.

In conclusion, Ambisome is an effective medication for treating fungal infections. To ensure its safe and optimal use, it is important to follow the prescribed dosage, receive the medication through intravenous infusion, maintain hydration, undergo regular monitoring and blood tests, be aware of potential side effects, consider drug interactions, and discuss the usage during pregnancy or breastfeeding with your healthcare provider. By following these guidelines, you can maximize the effectiveness of Ambisome while minimizing any potential risks. Remember to always consult with your healthcare provider for personalized advice and guidance regarding your specific situation.