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Ambisome(安必素)出现副作用如何处理

发布时间:2024-02-06 12:59:49 阅读:1034 来源:问药网
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安必素

安必素 生产厂家:美国吉利德科学公司(Gilead Sciences) 功能主治:一线抗真菌药物,治疗深部真菌感染有效率高 用法用量:用法用量  静脉用药:开始静脉滴注时先试以1~5mg或按体重一次0.02~0.1mg/kg给药,以后根据患者耐受情况每日或隔日增加5mg,当增至一次 0.6~0.7mg/kg时即可暂停增加剂量,此为一般治疗量。  成人最高一日剂量不超过1mg/kg,每日或隔1~2日给药1次,累积总量 1.5~3.0g,疗程1~3个月,也可长至6个月,视病情及疾病种类而定。  对敏感真菌感染宜采用较小剂量,即成人一次20~30mg,疗程仍宜长。  鞘内给药:首次0.05~0.1mg,以后渐增至每次0.5mg,最大量一次不超过1mg,每周给药2~3次,总量15mg左右。  鞘内给药时宜与小剂量地塞米松或琥珀酸氢化可的松同时给与,并需用脑脊液反复稀释药液,边稀释边缓慢注入以减少不良反应。  局部用药:气溶吸入时成人每次5~10mg,用灭菌注射用水溶解成0.2%~0.3%溶液应用;超声雾化吸入时本品浓度为0.01%~0.02%,每日吸入2~3次,每次吸入5~10ml;持续膀胱冲洗时每日以两性霉素B 5mg加入1000ml灭菌注射用水中,按每小时注入40ml速度进行冲洗,共用5~10日。  静脉滴注或鞘内给药时,均先以灭菌注射用水10ml配制本品50mg,或5ml配制25mg,然后用5%葡萄糖注射液稀释(不可用氯化钠注射液,因可产生沉淀),滴注液的药物浓度不超过10mg/100ml,避光缓慢静滴,每次滴注时间需6小时以上,稀释用葡萄糖注射液的pH值应在4.2以上。  鞘内注射时可取5mg/ml浓度的药液1ml,加5%葡萄糖注射液19ml稀释,使最终浓度成250μg/ml。  注射时取所需药液量以脑脊液5~30ml反复稀释,并缓慢注入。  鞘内注射液的药物浓度不可高于25mg/100ml,pH值应在4.2以上。
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Ambisome(安必素)出现副作用如何处理,Ambisome(AmBisome)常见副作用包括发热、寒战、呼吸困难、恶心、呕吐、肾功能损害、低钾血症、头痛和胃肠不适。在治疗期间需要监测肾功能和电解质。Ambisome(AmBisome)是一种抗真菌药物,其主要成分是阿莫夫洛星(AmphotericinB)。它主要用于治疗严重的真菌感染,具有以下疗效:1.抗真菌活性,抑制多种真菌的生长和繁殖。2.治疗各种念珠菌感染。3.治疗血液系统真菌感染。该药品在治疗相关疾病方面表现出色,疗效显著、安全性高。

Ambisome (安必素) is a medication used for the treatment of fungal infections. However, like any medication, it can sometimes cause side effects in certain individuals. It is important to understand how to handle these side effects to ensure the safety and well-being of patients. In this article, we will explore how to deal with the side effects that may arise from the use of Ambisome.

1. Understanding the Common Side Effects

When taking Ambisome, it is crucial to be aware of the common side effects that may occur. These side effects can include fever, chills, headache, muscle pain, nausea, vomiting, and changes in kidney function. By knowing what to expect, patients can be better prepared to handle these effects if they arise.

2. Contacting Your Healthcare Provider

If you experience any side effects while taking Ambisome, it is important to contact your healthcare provider immediately. They will be able to evaluate your symptoms and provide appropriate guidance. Do not hesitate to seek medical attention if you are concerned about any changes in your health.

3. Following Medical Advice

Your healthcare provider will provide specific instructions on how to manage the side effects of Ambisome. It is crucial to follow their advice diligently. They may recommend over-the-counter medications to alleviate certain symptoms or adjust your dosage to minimize side effects. Always consult with your healthcare provider before making any changes to your treatment plan.

4. Maintaining Proper Hydration

Some side effects of Ambisome, such as changes in kidney function, can be managed by maintaining proper hydration. Drinking an adequate amount of water throughout the day can help flush out any toxins and support kidney function. It is important to follow your healthcare provider's guidance regarding fluid intake to ensure optimal effectiveness of the medication and minimize side effects.

5. Monitoring for Severe Side Effects

While most side effects of Ambisome are mild and temporary, there is a possibility of more severe reactions in rare cases. It is crucial to monitor your symptoms and seek immediate medical attention if you experience any severe side effects such as severe allergic reactions, difficulty breathing, or severe changes in kidney function. Prompt action can help prevent further complications.

In conclusion, understanding and managing the side effects of Ambisome is important to ensure effective treatment of fungal infections. By being aware of the common side effects, contacting your healthcare provider, following medical advice, maintaining proper hydration, and monitoring for severe side effects, you can navigate the potential challenges that may arise from the use of this medication. Remember to always consult with your healthcare provider for personalized guidance regarding your specific situation.