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Baricitinib(巴瑞替尼)艾乐明有哪些注意事项和副作用

发布时间:2024-04-26 11:10:50 阅读:1094 来源:问药网
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巴瑞替尼片

巴瑞替尼片 生产厂家:孟加拉碧康制药股份有限公司 功能主治:对一种或多种抗风湿药物缓解不足或不耐受的中度至重 用法用量:用法用量  1、类风湿性关节炎  OLUMIANT的推荐剂量为每日1次口服2mg,餐前餐后都可。  OLUMIANT可以单独使用,也可以与甲氨蝶呤或其他非生物dmard联合使用。  2、COVID-19(新冠病毒)  成人OLUMIANT的推荐剂量为每日一次口服4mg,餐前餐后都可,持续14天或直到出院,以先发生者为准。  3、斑秃  OLUMIANT的推荐剂量是2mg,每天一次口服,餐前餐后都可。  如果对治疗的反应不充分,增加到每天一次4mg。  对于几乎完全或完全的头皮脱发,睫毛或眉毛有或没有大量脱发的患者,考虑每天一次4mg治疗,伴餐前餐后都可。  一旦患者对4mg的治疗产生了充分的反应,将剂量减少到2mg,每天一次。  对于无法吞下整片药片的患者,可以考虑另一种给药方式:  1、口服分散  2、胃造口管(G管)  3、鼻胃管(NG管)或口胃管(OG管)
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Baricitinib(巴瑞替尼)艾乐明有哪些注意事项和副作用,Baricitinib(Baricitinib)常见副作用有:1、严重感染,如肺炎、带状疱疹和尿路感染;2、死亡率,50岁以上及有心血管疾病的患者有更高的全因死亡率;3、恶性肿瘤和淋巴增生性疾病;4、重大心血管不良事件;5、血栓形成;6、会出现过敏反应;7、胃肠道穿孔;8、可能会对胎儿造成损害。

Baricitinib (巴瑞替尼) is a medication primarily used for the treatment of rheumatoid arthritis, COVID-19, and alopecia areata. It belongs to a class of drugs called Janus kinase (JAK) inhibitors and works by suppressing the immune response. While baricitinib has shown effectiveness in managing certain conditions, it is crucial to be aware of certain precautions and potential side effects associated with its use. This article will provide an overview of the precautions and side effects of baricitinib.

1. Precautions for Baricitinib:

Before starting baricitinib treatment, it is important to inform your healthcare provider about any existing medical conditions, allergies, or medications you are taking. Your doctor will evaluate these factors to determine if baricitinib is suitable for you. Additionally, consider the following precautions:

a. Infections: Baricitinib may increase the risk of developing serious infections. It is advised to avoid the use of baricitinib in individuals with active infections or chronic, recurrent infections. Inform your doctor if you experience symptoms of an infection, such as fever, cough, or difficulty breathing.

b. Tuberculosis: Patients should be screened for latent tuberculosis before initiating baricitinib, as it can reactivate the infection. If you have a history of tuberculosis or have been in close contact with someone with tuberculosis, discuss this with your doctor.

c. Hepatitis B or C: Patients with known hepatitis B or C infections should be closely monitored during treatment with baricitinib. The medication may worsen liver function in these individuals.

d. Vaccinations: Prior to commencing baricitinib, ensure that you are up to date with vaccinations, including the COVID-19 vaccine. However, live vaccines should be avoided while taking baricitinib.

2. Side Effects of Baricitinib:

While baricitinib can be beneficial for managing certain conditions, it is essential to be aware of potential side effects that may arise during treatment. Common side effects include:

a. Infections: As mentioned earlier, baricitinib may increase the risk of infections. Watch for signs of infection and promptly inform your healthcare provider if any symptoms occur.

b. Increased cholesterol levels: Baricitinib can cause elevations in cholesterol levels, particularly low-density lipoprotein (LDL) cholesterol. Regular monitoring of cholesterol levels is advisable.

c. Blood clotting: There have been reports of blood clotting events, including deep vein thrombosis and pulmonary embolism, in patients taking baricitinib. Seek medical attention immediately if you experience symptoms such as sudden chest pain, shortness of breath, or leg swelling.

d. Allergic reactions: In rare cases, baricitinib may cause allergic reactions. If you develop hives, rash, itching, swelling, difficulty breathing, or dizziness, seek immediate medical attention.

e. Other side effects: Baricitinib can also cause headache, nausea, diarrhea, and changes in liver function tests. If you experience any unusual or persistent side effects, inform your doctor.

It is important to note that this list of side effects is not exhaustive, and individual experiences may vary. Always consult with your healthcare provider for personalized advice and guidance regarding the use of baricitinib.

In conclusion, baricitinib is a medication used for the treatment of rheumatoid arthritis, COVID-19, and alopecia areata. However, like any medication, it is associated with precautions and potential side effects. By being aware of these considerations and discussing them with your healthcare provider, you can make informed decisions about your treatment and manage any possible risks effectively.