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Ambisome(安必素)怎么贮存

发布时间:2024-12-11 17:35:20 阅读:1065 来源:问药网
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安必素

安必素 生产厂家:美国吉利德科学公司(Gilead Sciences) 功能主治:一线抗真菌药物,治疗深部真菌感染有效率高 用法用量:用法用量  静脉用药:开始静脉滴注时先试以1~5mg或按体重一次0.02~0.1mg/kg给药,以后根据患者耐受情况每日或隔日增加5mg,当增至一次 0.6~0.7mg/kg时即可暂停增加剂量,此为一般治疗量。  成人最高一日剂量不超过1mg/kg,每日或隔1~2日给药1次,累积总量 1.5~3.0g,疗程1~3个月,也可长至6个月,视病情及疾病种类而定。  对敏感真菌感染宜采用较小剂量,即成人一次20~30mg,疗程仍宜长。  鞘内给药:首次0.05~0.1mg,以后渐增至每次0.5mg,最大量一次不超过1mg,每周给药2~3次,总量15mg左右。  鞘内给药时宜与小剂量地塞米松或琥珀酸氢化可的松同时给与,并需用脑脊液反复稀释药液,边稀释边缓慢注入以减少不良反应。  局部用药:气溶吸入时成人每次5~10mg,用灭菌注射用水溶解成0.2%~0.3%溶液应用;超声雾化吸入时本品浓度为0.01%~0.02%,每日吸入2~3次,每次吸入5~10ml;持续膀胱冲洗时每日以两性霉素B 5mg加入1000ml灭菌注射用水中,按每小时注入40ml速度进行冲洗,共用5~10日。  静脉滴注或鞘内给药时,均先以灭菌注射用水10ml配制本品50mg,或5ml配制25mg,然后用5%葡萄糖注射液稀释(不可用氯化钠注射液,因可产生沉淀),滴注液的药物浓度不超过10mg/100ml,避光缓慢静滴,每次滴注时间需6小时以上,稀释用葡萄糖注射液的pH值应在4.2以上。  鞘内注射时可取5mg/ml浓度的药液1ml,加5%葡萄糖注射液19ml稀释,使最终浓度成250μg/ml。  注射时取所需药液量以脑脊液5~30ml反复稀释,并缓慢注入。  鞘内注射液的药物浓度不可高于25mg/100ml,pH值应在4.2以上。
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Ambisome(安必素)怎么贮存,Ambisome(AmBisome)贮存条件为:25摄氏度以下避光贮藏。置于儿童不可接触的地方。

Title: Storage Guidelines for Ambisome: Ensuring Optimal Treatment for Fungal Infections

Introduction:

Ambisome is a medication used to treat fungal infections caused by various types of fungi. Proper storage of Ambisome is essential to maintain its effectiveness and ensure patient safety. In this article, we will provide accurate answers and guidelines for the storage of Ambisome.

1. Understanding Ambisome Storage Requirements:

Proper storage conditions are vital for the stability and effectiveness of Ambisome. It is important to store Ambisome according to the manufacturer's instructions and in compliance with pharmacy regulations. Improper storage may result in the degradation of the medication and compromise its therapeutic benefits.

2. Temperature and Ambient Conditions:

Ambisome should be stored at a controlled room temperature between 20°C and 25°C (68°F and 77°F). It is crucial to avoid exposure to extreme heat, freezing temperatures, and direct sunlight. Storing Ambisome in a cool, dry place is recommended to maintain its integrity and prolong its shelf life.

3. Packaging and Protection:

Ambisome comes in vials or bags for intravenous administration. The packaging should remain intact until it is time for use. Ensure that the vials or bags are not damaged, leaking, or compromised in any way. If you notice any abnormalities with the packaging, contact your healthcare provider or pharmacist immediately.

4. Proper Handling and Storage:

Ambisome should be stored out of reach of children and pets. Additionally, it is important to keep Ambisome away from other medications to prevent any possible cross-contamination. Store Ambisome in a secure area, such as a locked cabinet or cupboard, to minimize the risk of unauthorized access or accidental ingestion.

5. Avoid Freezing and Thawing:

Ambisome should not be frozen. Freezing the medication can cause structural changes, which may result in reduced effectiveness. If the medication accidentally freezes, do not use it, and consult your healthcare professional or pharmacist for further guidance.

6. Disposal of Expired or Unused Ambisome:

Do not use Ambisome beyond its expiration date. Expired medications may not provide the intended therapeutic benefits and can be potentially harmful. Properly dispose of expired or unused Ambisome as per local regulations or consult your healthcare provider or pharmacist for guidance on safe disposal methods.

Conclusion:

Proper storage of Ambisome is crucial for maintaining its effectiveness in treating fungal infections. Adhering to the storage guidelines, such as maintaining proper temperature, protecting from light, and ensuring secure packaging, will help preserve the quality and potency of the medication. If you have any questions or concerns regarding the storage of Ambisome, seek guidance from your healthcare provider or pharmacist.