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Ambisome(安必松)安必素每次吃多少

发布时间:2025-02-16 08:17:51 阅读:1506 来源:问药网
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安必素

安必素 生产厂家:美国吉利德科学公司(Gilead Sciences) 功能主治:一线抗真菌药物,治疗深部真菌感染有效率高 用法用量:用法用量  静脉用药:开始静脉滴注时先试以1~5mg或按体重一次0.02~0.1mg/kg给药,以后根据患者耐受情况每日或隔日增加5mg,当增至一次 0.6~0.7mg/kg时即可暂停增加剂量,此为一般治疗量。  成人最高一日剂量不超过1mg/kg,每日或隔1~2日给药1次,累积总量 1.5~3.0g,疗程1~3个月,也可长至6个月,视病情及疾病种类而定。  对敏感真菌感染宜采用较小剂量,即成人一次20~30mg,疗程仍宜长。  鞘内给药:首次0.05~0.1mg,以后渐增至每次0.5mg,最大量一次不超过1mg,每周给药2~3次,总量15mg左右。  鞘内给药时宜与小剂量地塞米松或琥珀酸氢化可的松同时给与,并需用脑脊液反复稀释药液,边稀释边缓慢注入以减少不良反应。  局部用药:气溶吸入时成人每次5~10mg,用灭菌注射用水溶解成0.2%~0.3%溶液应用;超声雾化吸入时本品浓度为0.01%~0.02%,每日吸入2~3次,每次吸入5~10ml;持续膀胱冲洗时每日以两性霉素B 5mg加入1000ml灭菌注射用水中,按每小时注入40ml速度进行冲洗,共用5~10日。  静脉滴注或鞘内给药时,均先以灭菌注射用水10ml配制本品50mg,或5ml配制25mg,然后用5%葡萄糖注射液稀释(不可用氯化钠注射液,因可产生沉淀),滴注液的药物浓度不超过10mg/100ml,避光缓慢静滴,每次滴注时间需6小时以上,稀释用葡萄糖注射液的pH值应在4.2以上。  鞘内注射时可取5mg/ml浓度的药液1ml,加5%葡萄糖注射液19ml稀释,使最终浓度成250μg/ml。  注射时取所需药液量以脑脊液5~30ml反复稀释,并缓慢注入。  鞘内注射液的药物浓度不可高于25mg/100ml,pH值应在4.2以上。
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Ambisome(安必松)安必素每次吃多少,Ambisome(AmBisome)建议在新的治疗疗程之前给予测试剂量。可以服用少量的AmBisome输液(例如1mg)约10分钟,然后停止服用,并在接下来的30分钟内仔细观察患者。如果没有严重的过敏或类过敏反应,则可以继续输注AmBisome剂量。

Ambisome (安必松), also known as amphotericin B lipid complex, is a medication commonly used for the treatment of fungal infections. It is administered intravenously and serves as an important tool in combating severe fungal infections. The dosage of Ambisome varies depending on several factors, including the type and severity of the infection, the patient's overall health condition, and their response to the treatment. It is crucial to follow the prescribed dosage regimen recommended by your healthcare provider for optimal therapeutic results.

1. Importance of Accurate Dosage

Accurate dosage of Ambisome is crucial for its effectiveness in treating fungal infections. It is important to note that Ambisome is a potent medication with potential side effects, and improper dosing can lead to adverse reactions or treatment failure. Therefore, it is vital to adhere to the prescribed dosage and follow the instructions provided by your healthcare provider or pharmacist.

2. Individualized Dosage Regimen

The dosage of Ambisome is typically calculated based on the patient's body weight and renal function. Your healthcare provider will assess these factors to determine the appropriate dosage for you. Generally, the recommended dose of Ambisome ranges from 3 to 5 mg per kilogram of body weight per day. However, the exact dosage and treatment duration may vary depending on the specific infection and individual circumstances. Your healthcare provider will closely monitor your progress and adjust the dosage accordingly.

3. Treatment Duration and Frequency

The treatment duration and frequency of Ambisome administration also depend on the infection being treated. In some cases, the medication may be given daily, while in others, it may be administered every other day or a few times a week. The total duration of treatment can range from several weeks to several months. It is essential to complete the full course of treatment as prescribed, even if symptoms improve before the treatment is finished. Prematurely stopping the medication can lead to the recurrence of the infection or the development of drug-resistant strains.

4. Administration Process and Monitoring

Ambisome is administered intravenously under the supervision of healthcare professionals. The infusion usually takes about 2 hours to complete. Throughout the treatment, your healthcare provider will monitor your vital signs, kidney function, and electrolyte levels to ensure your safety and the effectiveness of the medication. It is essential to communicate any concerns or side effects experienced during the treatment to your healthcare team promptly.

In conclusion, the accurate dosage of Ambisome is essential for effective treatment of fungal infections. The specific dosage will be determined by your healthcare provider based on various factors. It is crucial to strictly follow the prescribed dosage regimen and complete the full course of treatment to maximize its benefits. Remember to consult your healthcare provider or pharmacist for any questions or concerns regarding the appropriate dosage of Ambisome for your specific condition.